Identification of tumor-associated antigens in human thyroid papillar carcinoma
نویسندگان
چکیده
منابع مشابه
[Giant metastasis of thyroid papillar carcinoma].
O carcinoma papilífero da tireoide, o mais comum deste órgão, geralmente se apresenta como lesões parenquimatosas pequenas e, eventualmente, com metástases cervicais numerosas, raramente volumosas. É descrito um caso raro de uma paciente do gênero feminino, 44 anos, com um tumor cervical anterior, nodular e volumoso há nove anos. Após o tratamento cirúrgico, o anatomopatológico mostrou tratar-s...
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Hepatocellular carcinoma (HCC) is a major cause of death in Asian countries. The false-negative rate with serum alpha-fetaprotein level alone can reach 40% for early stage HCC patients. Due to the lack of sensitive and specific tumor markers for early diagnosis, it is impossible for HCC patients to receive effective therapy. However, tumor antigens can be recognized by immune cells and be rejec...
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Background & Objective: Papillary thyroid cancer (PTC) is considered to be the most common type of thyroid malignancies. Epigenetic alteration, in which the chromatin conformation and gene expression change without changing the sequence of DNA, can occur in some tumor suppressor genes and oncogenes. Methylation is the most common type of epigenetic alterations that can be an ex...
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Three human lung tumor-associated antigens (TAA's) have been identified in soluble and membrane-solubilized extracts of human squamous cell lung carcinoma with the use of antisera raised in rabbits. The antigens were identified and partially characterized by means of an agarose adsorption technique. These antigens, termed lung TAA's 1,2, and 3, are all soluble in 50% ammonium sulfate, are antig...
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Several studies have now clearly indicated the presence of tumor-associated and tumor-specific antigens in cells of human malignant melanoma. These antigens have been identified by means of several quite different techniques, including the use of antibodies detectable against the antigens, either by means of immunofluorescence, (1-5) cytotoxicity (4, 6, 7) or by extracting the antigen and obtai...
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ژورنال
عنوان ژورنال: Biopolymers and Cell
سال: 2003
ISSN: 0233-7657,1993-6842
DOI: 10.7124/bc.000681